Topical NSAID Effective For Knee Pain

NSAID (Non-Steroidal Anti-Inflammatory) is the group of drugs that includes familiar names such as Motrin (ibuprofen) and Aleve (Naproxen). NSAID by its anti-inflammatory action and being an analgesic (pain killer) is useful for treating conditions such as arthritis. While this article shows NSAID is as effective as oral medication for treating knee pain, patients with widespread pain preferred oral medications. This article while stating that oral medication had more side effects such as indigestion, increased blood pressure and asthma, it gave no information on the incidence of gastrointestinal bleed – one of the most serious concerns related to NSAID prescribing, be it oral or topical.

Topical NSAID As Effective As Tablets For Knee Pain
Medical News Today
Article Date: 18 Jun 2008 – 2:00 PDT

Research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has found that non-steroidal anti-inflammatory (NSAIDs) creams is as effective as tablets for the treatment of chronic knee pain in older people. Currently both topical and oral NSAID preparations of drugs like ibuprofen, naproxen and diclofenac, are used to treat knee pain. NSAIDs, however, are associated with gastrointestinal, cardiovascular and respiratory adverse effects, which are a particular risk for older people. Topical preparations should produce fewer side effects and so could be a good alternative treatment for this group of people. More…